Megan Fox is often associated with the term "Transformer" because of her breakout role in the Transformers film series, directed by Michael Bay. In the first two movies of the franchise (Transformers in 2007 and Transformers: Revenge of the Fallen in 2009), she played Mikaela Banes, the female lead and love interest of Shia LaBeouf's character, Sam Witwicky.

Her portrayal in the films, combined with their massive global success, catapulted her to international fame. Fans and media sometimes casually refer to her as "Transformer" or link her identity to the franchise because it was a defining moment in her career.

Despite leaving the series after the second film, her association with the Transformers brand remains strong in popular culture.